Our gene expression is influenced by nutrition and other environmental factors such as sleep, stress and physical activity. Understanding our genetics can help us understand where extra support may be required. Genetic test results, however, should not be considered in isolation and it’s important that results are analysed within a full support package. 

Genetic testing alongside functional testing will ensure your personalised plan is truly bespoke and based on a comprehensive understanding of your body and its systems.

When selecting genetic testing it’s vital to chose a reputable company. With this in mind, I have trained with Lifecode Gxand DnaLifeⓇ and can advise you which of their genetic test would be most suitable for you.

Lifecode GxProfiles Offered

Nutrient Core

 

Discover how genes impact: food response – gluten (coeliac disease), lactose (found in dairy), and caffeine; microbiome diversity; nutrient need – vitamin A (beta-carotene & retinol), folate (B9), vitamin B12, vitamin C, vitamin D, vitamin K, and glutathione; metabolism – blood sugar control (insulin), appetite (leptin), inflammation and omega-3 fatty acids; and circadian rhythm – early bird or night owl predisposition.

Metabolics

 

Metabolism describes the chemical reactions in the body involved in nutrient assimilation, utilisation – fat / sugar burning or storing – and removal. Presenting 6 interconnected pathways: appetite regulation, nutrient sensing, sugar metabolism, fat metabolism, cholesterol and bile, and mitochondria and inflammation. To help manage your personal risk of diabetes, chronic fatigue, weight gain, cardiovascular and neurodegenerative conditions and optimise health span and longevity.

Hormones

Steroids are hormones derived from cholesterol that act as chemical messengers in the body. They are involved in the regulation of many physiological processes in men and women, such as the function of the reproductive system, metabolism, inflammation and immune system. This test analyses genes involved in the synthesis, signalling, transport and metabolism of corticosteroids and sex steroids hormones.

Methylation

 

Methylation is critical to keeping your body and brain biochemistry in balance. Common genetic variants (SNPs) can impact methylation and increase susceptibility to systemic imbalances and chronic health conditions such as cardiovascular disease, sub-fertility, mood swings, depression, dementia, fatigue, autoimmune disease, allergies and premature ageing.

Histamine Intolerance

Histamine intolerance is a toxic response by the body resulting from an imbalance between accumulated histamine and the capacity to break it down. Symptoms of histamine toxicity may mimic an allergic reaction including skin irritation, gastro-intestinal upset, respiratory distress, headaches, insomnia and anxiety.

Oestrogen Balance

 

Oestrogen and androgen imbalances can contribute to sub-fertility, PCOS, endometriosis, menstrual irregularities, excess facial hair (women) or breast tissue (men), osteoporosis, cardio-vascular disease, blood clots, acne, sexual disfunction, mood swings, poor memory, weight gain and hormone sensitive cancers.

Detoxification

Genetic variants (SNPs) can impact phase 1, 2 and 3 detoxification pathways and contribute to symptoms such as headaches, muscle aches, fatigue, allergies, skin disorders, weight gain, bloating, acid reflux and heartburn, excessive sweating, chronic infections, sub-fertility, decreased libido, poor mental function and lower stress tolerance.

Nervous System

 

Neurotransmitters are chemicals that enable communication within and between neurons in the mind and body. Symptoms of neurotransmitter imbalance can include: mood imbalances, depression, mania, attention deficit and obsessive compulsive disorders, addictive behaviours, motor control disruption, anger, aggression and restlessness.

APOE

The APOE4 genotype is a well known risk factor for late onset Alzheimer’s disease and cardiovascular diseases. This test also analyses genes involved in the three subtypes of Alzheimer’s – i) inflammatory, ii) toxic and ii) atrophic – described in the BredesenTM protocol. Understanding your risk enables a personalised approach to managing it.

Thyroid

 

The thyroid is an endocrine gland in the neck that produces triiodothyronine (T3) and thyroxine (T4). Thyroid hormones control the metabolism of almost every cell, with wide- ranging metabolic, developmental and cardiovascular effects. This report analyses genes involved in the thyroid hormone lifecycle: synthesis, activation, transport and metabolism. It also examines genes that confer susceptibility to inflammation and autoimmunity.

Athlete

Whether you are an elite athlete, a ‘weekend warrior’, or just want to be more active, the athlete DNA test will enable you to optimise: 1.Training – cardio-vascular adaption, strategic fuelling and structural strength; 2. Recovery – build resilience and reduce injury risk; and 3. Performance – balance stress and stimulation – to achieve your personal best.

Nutrient Core

Discover how genes impact: food response – gluten (coeliac disease), lactose (found in dairy), and caffeine; microbiome diversity; nutrient need – vitamin A (beta-carotene & retinol), folate (B9), vitamin B12, vitamin C, vitamin D, vitamin K, and glutathione; metabolism – blood sugar control (insulin), appetite (leptin), inflammation and omega-3 fatty acids; and circadian rhythm – early bird or night owl predisposition.

Metabolics

Metabolism describes the chemical reactions in the body involved in nutrient assimilation, utilisation – fat / sugar burning or storing – and removal. Presenting 6 interconnected pathways: appetite regulation, nutrient sensing, sugar metabolism, fat metabolism, cholesterol and bile, and mitochondria and inflammation. To help manage your personal risk of diabetes, chronic fatigue, weight gain, cardiovascular and neurodegenerative conditions and optimise health span and longevity.

Hormones

Steroids are hormones derived from cholesterol that act as chemical messengers in the body. They are involved in the regulation of many physiological processes in men and women, such as the function of the reproductive system, metabolism, inflammation and immune system. This test analyses genes involved in the synthesis, signalling, transport and metabolism of corticosteroids and sex steroids hormones.

Methylation

Methylation is critical to keeping your body and brain biochemistry in balance. Common genetic variants (SNPs) can impact methylation and increase susceptibility to systemic imbalances and chronic health conditions such as cardiovascular disease, sub-fertility, mood swings, depression, dementia, fatigue, autoimmune disease, allergies and premature ageing.

Histamine Intolerance

Histamine intolerance is a toxic response by the body resulting from an imbalance between accumulated histamine and the capacity to break it down. Symptoms of histamine toxicity may mimic an allergic reaction including skin irritation, gastro-intestinal upset, respiratory distress, headaches, insomnia and anxiety.

Oestrogen Balance

Oestrogen and androgen imbalances can contribute to sub-fertility, PCOS, endometriosis, menstrual irregularities, excess facial hair (women) or breast tissue (men), osteoporosis, cardio-vascular disease, blood clots, acne, sexual disfunction, mood swings, poor memory, weight gain and hormone sensitive cancers.

Detoxification

Genetic variants (SNPs) can impact phase 1, 2 and 3 detoxification pathways and contribute to symptoms such as headaches, muscle aches, fatigue, allergies, skin disorders, weight gain, bloating, acid reflux and heartburn, excessive sweating, chronic infections, sub-fertility, decreased libido, poor mental function and lower stress tolerance.

Nervous System

Neurotransmitters are chemicals that enable communication within and between neurons in the mind and body. Symptoms of neurotransmitter imbalance can include: mood imbalances, depression, mania, attention deficit and obsessive compulsive disorders, addictive behaviours, motor control disruption, anger, aggression and restlessness.

APOE

The APOE4 genotype is a well known risk factor for late onset Alzheimer’s disease and cardiovascular diseases. This test also analyses genes involved in the three subtypes of Alzheimer’s – i) inflammatory, ii) toxic and ii) atrophic – described in the BredesenTM protocol. Understanding your risk enables a personalised approach to managing it.

Thyroid

The thyroid is an endocrine gland in the neck that produces triiodothyronine (T3) and thyroxine (T4). Thyroid hormones control the metabolism of almost every cell, with wide- ranging metabolic, developmental and cardiovascular effects. This report analyses genes involved in the thyroid hormone lifecycle: synthesis, activation, transport and metabolism. It also examines genes that confer susceptibility to inflammation and autoimmunity.

Athlete

Whether you are an elite athlete, a ‘weekend warrior’, or just want to be more active, the athlete DNA test will enable you to optimise: 1.Training – cardio-vascular adaption, strategic fuelling and structural strength; 2. Recovery – build resilience and reduce injury risk; and 3. Performance – balance stress and stimulation – to achieve your personal best.

Nutrigenomics Q & A

What is Nutrigenomics?

Nutrigenomics is the study of interactions between genes, nutrients and health. A nutrigenomics test examines DNA to identify variants that can impact your health, but can be supported by nutrition and other lifestyle factors.

How will it help me?

Nutrigenomics enables a preventative, personalised, and proactive approach to health. The test results can inform everyday decisions such as eliminating some foods or adding others – instead of a ‘one-size-fits all’ approach.

When should I do it?

A nutrigenomics test can be done at any age, from one day old to a hundred years young. The earlier you test the sooner you can tailor your diet and lifestyle to work with and support your genetics.

How accurate is it?

The genotyping data is more than 99.9% accurate. However, the interpretation of the results can vary from company to company. Lifecode Gx qualified nutritional therapists and nutrigenomics specialists ensure accurate, evidence-based, interpretation of results alongside clinically and practically relevant recommendations. This knowledge empowers you to make informed choices.

How does it work?

A simple cotton swab is provided to collect loose cells from the inside of your mouth. It is sent off to a lab for analysis, and the results are ready two to three weeks later.

Do I need to get re-tested?

No, you don’t need do the same test again – as your genes are fixed – your genetic code doesn’t change throughout your lifetime. You may choose to do additional tests in the future to assess different genes.

Who are Lifecode Gx?

Lifecode Gx is the UK’s leading provider of clinically relevant, nutrigenomics testing services, applying the latest nutrigenomics research to enable a personalised approach to health. We work exclusively with health professionals to ensure clients get the most benefit from their tests.

What are the different types of tests?

Lifecode Gx offers a range of 10 DNA test panels – Nutrient Core, Hormones, Methylation, Histamine Intolerance, Oestrogen Balance, Detoxification, Nervous System, APOE, Thyroid Balance, and Athlete.

What happens to my data?

At Lifecode Gx, data privacy and protection is our priority. Your data is safe, secure and confidential. Samples are anonymised, and the data is used exclusively to produce your personalised nutrigenomics report(s). Your sample is destroyed after 3 months, and your data will never be shared or sold.

Reference: https://www.lifecodegx.com

Lifecode GxⓇ Pricing

DNA test kit cost: £99

You only need to pay for one test kit regardless of how many profiles you select.

Prices below do not include test kit.

So if selecting 1 profile the total cost would be £150 + £99 = £249, or selecting 2 profiles the cost would be £300 + £99 = £399 etc.

1 profile £150

2 profiles £300

3 profiles £450

4 profiles £600

5 profiles £732*

* Discounted price for 5th panel

Results discussed within a one to one consultation

£100 per hour